Hyperspectral imaging in detecting dermal invasion in lentigo maligna melanoma

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Hyperspectral imaging in detecting dermal invasion in lentigo maligna melanoma.

N. Neittaanmäki, M. Salmivuori, I. Pölönen, L. Jeskanen, A. Ranki, O. Saksela, E. Snellman, M. Grönroos (1) Department of Clinical Pathology, Sahlgrenska University hospital, Göteborg, Sweden (2) Department of Dermatology and Allergology, Päijät-Häme Social and Health Care Group, Lahti, Finland (3) Department of Mathematical Information Technology, University of Jyväskylä, Finland (4) Departmen...

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Lentigo maligna (LM) is a pigmented lesion that occurs on the sun-exposed skin, particularly the head and neck areas, of an older patient. The lesion increases in size and at some point, often many years after its onset, may become lentigo maligna melanoma (LMM). For this reason, most authors consider LM a form of melanoma in situ. Treatment includes surgical or destructive modalities; the pref...

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Angiocentric invasion by lentigo maligna melanoma.

A case of angiocentric invasion by a lentigo maligna melanoma is reported. Pericapillary cuffing and permeative intimal expansion of veins by melanoma without luminal tumour cell emboli, thrombosis, or vascular destruction were associated with a lentigo maligna melanoma on the face of a 93 year old woman. This unusual infiltrative pattern suggests a specific interaction between melanoma cells a...

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Treatment of lentigo maligna and lentigo maligna melanoma.

Thirty-eight cases of lentigo maligna and 22 cases of lentigo maligna melanoma, were reviewed in order to compare cure rates of various methods of treatment. Surgical excision resulted in the best cure rate (91%); destructive modalities were less successful (45%). All lesions treated with 5% 5-fluorouracil recurred.

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Delineating margins of lentigo maligna using a hyperspectral imaging system.

Lentigo maligna (LM) is an in situ form of melanoma which can progress into invasive lentigo maligna melanoma (LMM). Variations in the pigmentation and thus visibility of the tumour make assessment of lesion borders challenging. We tested hyperspectral imaging system (HIS) in in vivo preoperative delineation of LM and LMM margins. We compared lesion margins delineated by HIS with those estimate...

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ژورنال

عنوان ژورنال: British Journal of Dermatology

سال: 2017

ISSN: 0007-0963

DOI: 10.1111/bjd.15267